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Year : 2012  |  Volume : 1  |  Issue : 3  |  Page : 166-168

Panniculitis-polyarthritis-pancreatitis syndrome

Department of Medicine, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India

Correspondence Address:
Swati C Aundhakar
Prof. Aundhakar C. Swati, Saurabh Hospital 140, Budhwar Peth, Karad, Satara, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-0521.106089

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Panniculitis and polyarthritis may rarely complicate a pancreatic disease; this association is defined as PPP-syndrome and is characterized by significant morbidity and mortality. Panniculitis is related to subcutaneous (liquefactive) fat necrosis with secondary skin changes due to the local activity of pancreatic enzymes released during different pancreatic diseases (inflammatory, acute and chronic, and neoplastic). The reported incidence of association of panniculitis and pancreatitis is 2-3% of all pancreatic diseases, while the complete PPP-syndrome is reported in very few cases. Here, we report a 49-year-old man with acute on chronic pancreatitis who presented to us with abdominal pain, arthritis, and multiple subcutaneous swellings which were present all over the body (generalized) unlike the commonly reported below-knee distribution, and this is what makes our case different. Biopsy from the subcutaneous swellings revealed fat necrosis and USG abdomen showed features of pancreatitis.

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