Saudi Journal for Health Sciences

: 2012  |  Volume : 1  |  Issue : 3  |  Page : 166--168

Panniculitis-polyarthritis-pancreatitis syndrome

Sanket K Mahajan, Swati C Aundhakar, Makarand B Mane 
 Department of Medicine, Krishna Institute of Medical Sciences University, Karad, Maharashtra, India

Correspondence Address:
Swati C Aundhakar
Prof. Aundhakar C. Swati, Saurabh Hospital 140, Budhwar Peth, Karad, Satara, Maharashtra

Panniculitis and polyarthritis may rarely complicate a pancreatic disease; this association is defined as PPP-syndrome and is characterized by significant morbidity and mortality. Panniculitis is related to subcutaneous (liquefactive) fat necrosis with secondary skin changes due to the local activity of pancreatic enzymes released during different pancreatic diseases (inflammatory, acute and chronic, and neoplastic). The reported incidence of association of panniculitis and pancreatitis is 2-3% of all pancreatic diseases, while the complete PPP-syndrome is reported in very few cases. Here, we report a 49-year-old man with acute on chronic pancreatitis who presented to us with abdominal pain, arthritis, and multiple subcutaneous swellings which were present all over the body (generalized) unlike the commonly reported below-knee distribution, and this is what makes our case different. Biopsy from the subcutaneous swellings revealed fat necrosis and USG abdomen showed features of pancreatitis.

How to cite this article:
Mahajan SK, Aundhakar SC, Mane MB. Panniculitis-polyarthritis-pancreatitis syndrome.Saudi J Health Sci 2012;1:166-168

How to cite this URL:
Mahajan SK, Aundhakar SC, Mane MB. Panniculitis-polyarthritis-pancreatitis syndrome. Saudi J Health Sci [serial online] 2012 [cited 2023 Jun 4 ];1:166-168
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